How CBD and THC in Marijuana Work Together to Stop Cancer

Through the millennia, marijuana has been used for its medicinal properties by cultures around the world. In the United States today, more and more individuals are turning to medical marijuana as part of their overall plan tohealing the body naturally.

Marijuana for medical use is not legal in all states and on a federal level, it is illegal to use and carry marijuana for any reason. As more states jump on the legalization bandwagon, however, questions are surfacing as to how marijuana heals the body, especially when it comes to dis-eases like Breast Cancer.

The Endocannabinoid System

In the 1980’s two specific targets for THC (Tetrahydrocannabinol) were discovered in the body. We now call these targets cannabinoid receptors. Also discovered was the presence of
endocannabinoids in the body, substances that help bind and synthesize the THC in marijuana to the cannabinoid receptors. The process of THC-cannabinoid receptor binding and the widespread effects this phenomenon has on the body is part of what researchers call the Endocannabinoid System.

“We now know that the Endocannabiniod System regulates a lot of biological functions such as appetite, food intake, motor function, reproduction and many others and that is why the plant has such a wide therapeutic potential,” says Dr. Christine Sanchez, a molecular biologist at Compultense University in Madrid, Spain. Sanchez and her team have been studying cancer and cannabinoids for over a decade.

CBD is a Powerful Antioxidant

CBD stands for Cannabidiol and, unlike THC, CBD does not have a psychoactive effect on the brain. It is, however, considered to be a powerful anti-cancer agent. More specifically, research is discovering that CBD may affect the genes involved in the spread of cancer.

“We found this one compound had a specific effect on metastatic cancer cells, very aggressive tumor cells,” says Sean McAllister and Pierre Desprez of the San Francisco-based California Pacific Medical Center. “We find when you treat with [Cannabidiol], you down regulate the expression of this protein, and that inhibits the disease process.”

In another study conducted in Japan, CBD stopped the spread of aggressive Breast Cancer. CBD has also exhibited protective action against lung cancer, thyroid cancer, cervical cancer and liver disease and is said to protect the brain from stress and damage as well.

THC May Kill Cancer Cells

But CBD is not the only compound in the marijuana plant that works on cancer. THC, the psychoactive component of the plant, is thought to kill existing cancer cells as well.

“We observed that when we treated [astrocytoma, a type of brain tumor] cells with cannabinoids, the THC…was killing the cells in our Petrie dishes,” Dr. Sanchez says.  “We…decided to analyze these components in animal models of breast and brain tumors. The results we are obtaining are telling us that cannabinoids may be useful for the treatment of Breast Cancer.”

Sanchez and others have found that the most potent effects occurs when THC and CBD are combined to kill cancer in the cleanest way possible.

“Cells can die in different ways and after cannabinoid treatment, (cancer cells) were dying in the clean way,” Dr. Sanchez says.  “They were committing suicide which is something that you really want…”

“One of the advantages of cannabinoid -based medicines would be that they target specifically tumor cells,” continues Dr. Sanchez. “They don’t have any toxic effect on normal non-tumoral cells. This is an advantage with respect to standard chemotherapy, that targets basically everything.”

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