Feb. 2, 2023 — A new study suggests that following a healthy lifestyle is linked to slower memory decline in older adults, even in people with the apolipoprotein E4 (APOE4) gene, one of the strongest known risk factors for Alzheimer’s disease and related dementias.

A team of investigators in China analyzed 10-year data on over 29,000 older adults with an average age of 72 years. Of these, a fifth were carriers of the APOE4 gene.

The investigators created a healthy lifestyle score by combining how much participants engaged in six activities: healthy diet, regular exercise, active social contact, cognitive activity, nonsmoking, and avoiding…


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