By Gonzalo Laje, MD, as told to Kara Mayer Robinson

I’m a psychiatrist, board certified in child, adolescent, and adult psychiatry. After my own personal experience with depression during my 20s, I’ve been on a lifelong quest to both understand and help others.

I spent almost a decade at the National Institutes of Health searching for ways to predict which depression treatments may be most effective for different people. Today, I manage Washington Behavioral Medicine Associates, a group practice in Chevy Chase, MD, where we help patients of all ages with treatment-resistant depression, or TRD.

Here’s what you should know about TRD and…


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