Major depressive disorder is the most widespread mood disorder in the world. Also called clinical depression, or just depression, it’s when you have symptoms of low mood or hopelessness for at least 2 weeks. Scientists still don’t know what causes it. But they know that treating it is complex and that people who have it need more ways to feel better faster.
For about half a century, scientists have put a lot of effort into improving medications that target a small set of neurotransmitters. Those are chemicals in the brain — serotonin, norepinephrine, and dopamine in particular — that affect how…