Chances are your role as caregiver took shape even before your loved one with complement 3 (C3) glomerulopathy knew exactly what they were dealing with. The first symptoms of this condition – blood and protein in the urine – can be signs of many other conditions. Investigating these symptoms to get a clear diagnosis can require several different tests. Ultimately, the diagnosis of C3G requires a kidney biopsy.

“C3 glomerulopathy can be a diagnostic challenge,” says Kirk Campbell, MD, professor of medicine at Icahn School of Medicine at Mount Sinai. “Leading up to the diagnosis, symptoms such as edema from fluid…


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