When you have multiple sclerosis (MS), your immune system works against you. Left unchecked, immune cells attack the protective layer that surrounds your nerve fibers. Doctors used to think your immune T cells were the main culprit in this. Immune B cells, which make antibodies, were considered innocent bystanders.

That changed as scientists started to realize that the existing MS treatments worked in part by changing what B cells were doing. Would it be possible to treat MS by targeting B cells directly?

Doctors already had a way to do it: an antibody-based treatment called rituximab, used to fight a type of…


By prebo

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